Oncogenesis Radiation

Radiation oncogenesis is the process of formation of malignant tumors under the influence of ionizing radiation, primarily radiation. Being under the destructive influence of radiation, cells when damaged mutate and become cancerous. This process is called radiosensitivity.

Back in the 50s, a connection was established between malignant neoplasms and radiation therapy. This issue has been studied in detail by such scientists as Kaczynski, Burnet, Whitehouse, and Schreyer. Malkin made a significant contribution to research on this topic.

When exposed to ionizing radiation, several processes of molecular and cellular restructuring occur in the human body:

1) Mutation of cells, in which case they can be transformed from epithelial cells into tumor cells without the development of normal structures. Normally, only cells of the nucleolar type are capable of transforming epithelial cells into malignant ones.

2) Cell fusion (leucantimal fusion). This type of transformation is more sensitive to radiation compared to mutation. As a result of fusion, large tumor structures are formed, since only in this case significant changes in the cellular composition occur. These forms are called syncytia

Radiation oncogenesis is a phenomenon in which exposure to radiation can cause the appearance of malignant tumors in the human body. This process occurs due to damage to the genetic material of the cell. When radiation destroys DNA, it can lead to changes in the cell's genetic material, which in turn can cause mutations and tumor development.

One of the most dangerous sources of radiation is radium, which is widely used in medicine to treat cancer. Radiation can cause cell growth in cancerous tissues, but it can also have negative effects on healthy cells in the body. It may