Granulosa cell tumor

Granulosa cell tumor is a disease that affects the female reproductive organs and can lead to serious complications.

Granulosa cell tumor (GCT) is a rare malignancy of granulosa cells derived from the primary gonad. It affects women of childbearing age – it begins at the age of 20 and is more common in women who smoke [1,3].

Globally, GCT accounts for one in 5 gonadal tumors in women under 35 years of age [2,4]

**Reasons for development**

Most cases are associated with sporadic ovarian lesions (99%), of which predominantly (more than 98%) are represented by male hormones that regulate the synthesis of enzymes involved in the synthesis of androgens from estrogens. Hormones can

Granulosa cell tumor is a neoplasm of the ovaries, characterized by the formation of nodules - cystadenofibrous (adamantgraafian) cysts, as well as benign tumors of the gland parenchyma. Includes a whole group of neoplasms of various morphological structures - granunocytoma with an epithelial structure, serous double-layer stromal tumor, cystadensfibroma, giant cystadenma, lymphoepithelial tumors, teratoma with derivatives of neuroblastoma. The term graneumoma was proposed in the middle of the 20th century, although this concept has certain historical background. Etiological