Osteoclastoma

According to the WHO definition, osteoclastomas are benign tumors arising from osteoclasts - giant multinucleated cells present in the bone marrow. This term is used more in the post-Soviet space and Australia.

Abroad, this tumor is called giant cell tumor (GCT). What does osteoclastoma consist of? Giant osteoblasts fill two-thirds of the entire cavity of the osteolytic cyst and are connected to each other by short processes. Among osteoblasts, individually located multilayered cubic giant multinucleated cells are most often located. In some cases, a large number of mononuclear giant oste are scattered

Osteoclastomas are malignant tumors that arise from mononuclear monocytes rather than from osteoblasts, which produce bone tissue. They usually consist of a base and a dome shape. Tumors are predominantly locally aggressive and are located in areas of bone mineralization. Less common are diffuse forms of osteoclastoma, localized in bone tissue without forming a mass. Diagnosis and treatment of osteoclasts is best carried out in specialized departments and by qualified specialists.