Paraagglutination

Paraagglutinin is a method for studying the specific interaction of microorganisms in antagonistic and agglutinogenic activity with the combined use of nutrient media of the same or similar compositions in the presence of an adsorbent (pumice, sand, slaked lime, trypsin).

M.E. Kazanskaya was one of the first domestic bacteriologists to study in detail the antagonistic activity of bacteria and identified its main properties: the common antigenic composition of colonists and antagonist; the same phase of cultural development; the formation of a certain interdependent complex “antagonists - colonists”.

The above-mentioned method of M.E. Kazanskaya and the method of paraagglutination developed by her is one of the most advanced methods for regulating the normobiosis of microbiological systems. Based on the author’s practical experience, the need arose to create specific isolated colonies of microbes as sources of high virulence, normal resistance to phages and pathogenic microorganisms when using antibiotics. M.E. Kazansky developed and proposed for industrial purposes a method for obtaining ideal (pathogen-free) plant vaccine preparations (lactic acid vaccine), taking into account the general and specific patterns of relationships between microbiocenoses (normal