Penetrance and expressivity of genetic alleles
**Gene penetrability** is a term introduced by biologist Rudolf Virchow in 1892 to designate the proportion of individuals with hidden manifestations of a trait. A mutation carrier is considered to be a person who does not have the disease. During the course of the disease, the ability and nature of perception of stress factors changes, which determine the reaction to a conflict situation at the neurotic, psychosomatic level. According to the hypothesis of internal tension, all stressful situations are divided into two groups:
* Intimate, involving the risk of loss, requiring the use of compensatory mechanisms and often disguised; * Non-intimate (family stress).
Genetic locus indicates a certain state of the psyche and mental activity. Thus, insulinoma is recognized as a protein genetic marker of inertia of thinking, intellectual inhibition