Poisoning with Cinchona Bark Alkaloids (Quinism)

Cinchona alkaloid poisoning, also known as quinism, is a serious complication that occurs when overdosing or taking too long of medications containing the alkaloid quinine.

Quinine is the main alkaloid isolated from the bark of the cinchona tree. It is widely used to treat malaria and several other diseases. However, toxic effects may occur if recommended doses are exceeded or if quinine is taken for a long time.

The main symptoms of poisoning with cinchona bark alkaloids:

1. Dizziness, headache
2. Nausea, vomiting, diarrhea
3. Tinnitus, hearing impairment
4. Visual impairment (blurred vision, photophobia)
5. Muscle cramps and twitching
6. Mental disorders (anxiety, depression)

In severe cases, poisoning can lead to coma, seizures, respiratory arrest and death. Long-term use of quinine in high doses increases the risk of irreversible damage to vision, hearing and the nervous system.

Treatment of quinism involves immediate discontinuation of quinine and supportive care. In some cases, hospitalization and intensive care for complications may be required.

Thus, quinine is an effective but potentially toxic drug. To avoid poisoning, it should be taken strictly as prescribed by a doctor and in no case exceed the recommended dose. If suspicious symptoms appear during treatment with quinine, you should immediately consult a doctor.

***Quinna poisoning, also known as poison XQ (chemical Quinism), has been associated with a risk of premature death in clinical trials of the drug. This is a serious event that requires urgent medical attention and rehabilitation.

***Symptoms of quinine poisoning include nausea, vomiting, diarrhea, dehydration, palpitations, convulsions, collapse, coma, seizure and sometimes death. Usually the patient continues to take quinine, which only worsens his condition. **This type of poisoning occurs not only from an overdose, but also from long-term use of quinine, since the effect appears slowly and does not make it possible to get rid of the drug.

**In case of acute poisoning, you should immediately stop taking quinine-containing drugs and consult a doctor for medical attention. The antidote quinine and other drugs such as N-acetylcysteine ​​may be considered. Severe cases may also require admission to an intensive care unit. It is important to understand that adequate treatment can significantly improve a patient's chances of survival.

***Quinine, also known as chemotherapy, is one of the most effective drugs for treating malaria. However, some side effects, such as quinine poisoning, can be serious and even fatal. Therefore, it is important to be aware of the potential risks and take precautions to avoid poisoning. If you are taking quinine as part of your primary therapy or prevention, use this medication only as directed by your doctor and actively collaborate with your doctor or health care professional about treatment and side effects. Do not delay seeking medical attention if you experience any strange symptoms that indicate a possible overdose or alcohol poisoning. Also keep in mind that you should not stop using the drug on your own without consulting your doctor.

Quinn bark alkaloid poisoning or Quinism is an acute and potentially fatal illness that occurs when too much quinna bark or its components are ingested in the human body. This is an infectious disease that results from taking excess amounts of quinine, similar to