Polyoxidine: a domestic drug for infusion therapy Introduction Plasma-substituting saline solutions are an important part of the pharmacy range, used to replenish blood deficiency and improve its composition in various diseases. Polyoxidine, or 33% solution of polyethylene oxide, is one of the most popular drugs in this group. It has a favorable price-quality ratio and extensive experience in use in medical institutions. In this article we will look in more detail at what Polyoxidin is and what it is used for.
Pharmacological action Polyoxide is a bulk plasma-substituting solution created on the basis of polyethylene glycol 300. The medicine has good effectiveness and is completely interchangeable in relation to native blood. The main function of the medicine is to replace blood loss and retain fluid during dehydration. The solution prevents blood thickening due to filtration through membranes and reduces platelet aggregation. Therefore, the active substances of Polyoxidine are: - Glycocolysis (dilution of blood to a specified volume) - Osmolality (obstruction to the combination of fluid in the circulatory system) - Ion replacement therapy (elimination of the lack of sodium and potassium ions in the body) In patients with dehydration or hemodynamic disorder, take Polyoxidine ensures smooth transcapillary fluid exchange, increases venous transport, reduces the permeability of the vascular wall and reduces blood viscosity by reducing hematocrit and increasing the body's water-removal function. It is known that Polyoxidine therapy has significant benefits for patients in cases where it is possible to reuse blood and other components during organ and/or cell transplantation. The effectiveness of the drug is assessed in terms of service life after a certain volume: depending on the length of stay, the patient must consume a certain amount of Polyoxidine solution and be under the supervision of an anesthesiologist or resuscitator. This usually takes place over several days. The main purpose of Polyoxidine is to carry out infusion treatment in patients of different age groups for the purpose of prevention, treatment and recovery from disorders of the respiratory system, in the treatment of various inflammatory diseases and pathologies that can cause complications, such as leukopenia, neutropenia and lymphocytopenia. Among the many advantages of Polyoxidine, there is a safety pharmacological effect, which gives a stable effect at the level of microcirculation, renal filtration, urine formation and protein content in it, reducing the concentration of urea in the blood,