Test with Tropaphen

The Tropaphen test is a method for diagnosing pheochromocytoma, which is based on the phenomenon of a decrease in blood pressure after intravenous administration of Tropaphen. This method was developed in the 1950s and has since been widely used in clinical practice.

The essence of the method is that in the presence of pheochromocytoma, which secretes catecholamines, vasoconstriction occurs, which leads to an increase in blood pressure. After administration of tropafen, which is an antagonist of adrenergic receptors, vasodilation occurs and blood pressure decreases.

The test with tropafen is carried out as follows: the patient is administered intravenously 0.1 mg of tropafen and after 15 minutes the blood pressure is measured. If after administration of tropafen there is a decrease in blood pressure by 20 mm Hg. Art. and more, this indicates the presence of pheochromocytoma.

However, the tropafen test has its limitations. It may not be effective if the amount of catecholamines released by the tumor is small, or if there are other causes of high blood pressure, such as kidney failure or hypertension.

In general, the Tropaphen test is a useful method for diagnosing pheochromocytoma and can be used to make the correct diagnosis and select effective treatment.

Introduction

Tropaphene test (PT) is a method for diagnosing fechromocytomas, tumor-like formations of the adrenal glands responsible for increased blood pressure. This test has high sensitivity and specificity, therefore it is the gold standard for diagnosing fechvomocytes. However, there are some problems when performing PST, and in this article we will look at the reasons why this test fails and possible solutions.

Description of the method

When performing PST, the patient is administered 0.5 mg of tropafen intravenously. It is a drug that acts as a ganglion blocker, reducing blood pressure and causing hypotension. After injection of tropafene Tindrek, observe the patient's reaction. The normal reaction is a decrease in blood pressure after the injection, which is restored after a few minutes. If after administration of tropefan blood pressure does not decrease during