Proton-Pump Inhibitor

A proton pump inhibitor (PPI) is a drug used to reduce gastric acid secretion by blocking the proton pump in the parietal cells of the stomach glands. One of the most common examples of PPI is omeprazole. These medications are used to treat gastric and duodenal ulcers, as well as reflux esophagitis.

How do proton pump inhibitors work?

Stomach hydrochloric acid plays an important role in the digestive process, helping to break down food and killing bacteria. However, some people may need to reduce their stomach acid levels. For example, with peptic ulcers of the stomach and duodenum, excess acid can cause burns and ulcers on the walls of the stomach and intestines. With reflux esophagitis, acid can back up into the esophagus, causing irritation and pain.

Proton pump inhibitors block the proton pump in the parietal cells of the stomach, resulting in decreased stomach acid levels. This may help reduce the risk of burns and ulcers and reduce symptoms of reflux esophagitis.

How to take proton pump inhibitors?

Proton pump inhibitors are usually taken once a day, 30-60 minutes before meals. The dosage may vary depending on the individual patient and the severity of the disease. Treatment usually continues for several weeks or months.

What side effects may occur when taking proton pump inhibitors?

Proton pump inhibitors are generally well tolerated by patients, but some may experience some side effects such as nausea, diarrhea, constipation, headache or fatigue. In rare cases, more serious side effects may occur with long-term use of proton pump inhibitors, such as decreased bone density and an increased risk of bone fractures.

Proton pump inhibitors are an important tool in the treatment of gastric and duodenal ulcers and reflux esophagitis. However, as with any medicine, it is important to consult a doctor and follow the instructions for use to avoid possible side effects. If you experience any unusual symptoms while taking proton pump inhibitors, be sure to tell your doctor.

Proton-Pump Inhibitor is a drug that reduces gastric acid secretion by blocking the proton pump in the parietal cells of the gastric glands.

Proton pump inhibitors include drugs such as omeprazole, lansoprazole, pantoprazole and others. They are widely used in medicine to treat various diseases associated with high stomach acidity.

Main indications for the use of proton pump inhibitors:

1. Peptic ulcer of the stomach and duodenum
2. Gastroesophageal reflux disease
3. Reflux esophagitis
4. Zollinger-Ellison syndrome
5. Prevention of aspirin gastropathy

These drugs suppress the secretion of hydrochloric acid in the stomach by 95-99%, providing a reliable antiulcer effect. They are well tolerated and are considered one of the most effective and safe means for long-term acid suppression.

Proton pump inhibitors: myths and reality

Proton pump inhibitors are a pharmacological group of medications that are used to reduce stomach acidity. High amounts of stomach acid can cause the acid to eat away at the stomach lining, impairing its functionality. But inhibitors do not work as primitively as they seem. They have almost the same effect on any people, but some doctors are categorically against their use. Is it so? Let's look at a list of ten myths about these drugs and get acquainted with the opinions of professional doctors