Pseudocholinesterase

Pseudocholinesterase is an enzyme that plays an important role in the breakdown of acetylcholine in the body. However, unlike cholinesterase, pseudocholinesterase works much more slowly.

Basically, pseudocholinesterase is found in the blood and other tissues of the body. Its function is to break down acetylcholine, which is an important neurotransmitter that transmits signals between nerve cells.

Although pseudocholinesterase may function to break down acetylcholine, it plays a relatively minor role in the normal breakdown of acetylcholine at synapses and neuromuscular junctions. This is due to the fact that this enzyme is absent in nerve endings.

Despite this, pseudocholinesterase has important medical significance. Some people have genetic variants that cause low levels of pseudocholinesterase in the body. This may result in a decrease in the rate at which acetylcholine is broken down, which can lead to a variety of unwanted effects, including prolonging the duration of action of anesthetics used during surgery.

In addition, pseudocholinesterase can be used as a biomarker for the diagnosis of certain diseases such as hepatitis and cirrhosis.

In conclusion, pseudocholinesterase is an important enzyme that plays an important role in the body, although its function in the normal breakdown of acetylcholine in nerve endings is not essential. However, this enzyme has important medical significance and can be used to diagnose certain diseases.

Pseudocholinesterase is an enzyme that is present in the blood and tissues of the body. It is similar to cholinesterase, but differs from it in the slow rate of breakdown of acetylcholine.

Pseudocholinesterase plays an important role in regulating the level of acetylcholine, which is a neurotransmitter in the nervous system. However, pseudocholinesterases are not present at nerve terminals and therefore play a lesser role in the breakdown of acetylcholine at synapses.

A deficiency of pseudocholinesterase can lead to increased levels of acetylcholine and the development of various diseases such as Alzheimer's and Parkinson's disease. Therefore, determining the level of pseudocholinesterase in the blood can be useful for diagnosing these diseases and assessing the effectiveness of treatment.

Overall, pseudocholinesterase is an important enzyme in the regulation of neurotransmitter levels and may be important for the diagnosis and treatment of various diseases of the nervous system.

Pseudocholinesterase is an enzyme produced by many species of protozoa. Like cholinerase, the enzymes rapidly hydrolyze acetycholine (and some other neurotransmitters), reducing its levels in nerve tissue. The activity of these enzymes does not depend on the concentration of adrenaline, inhibitory cofactors (Mg2+, Zn2+), as well as high thermolability (against the background of Choliner Az, activity remains up to 50 g/ml alcohol, the activity of pseudocholiner Ac is above 0.5 M HCl) In humans, pseudocholine Aa contains 7 isoforms, the main component of which is pseudocholinase. Most are found in neurons, lungs, red blood cells, platelets and plasma. A smaller fraction is found in leukocytes and brain tissue. Different isoforms of pseudocholineshfrvse have different rates of substrate degradation. AcetylchAlines (acetylamdiene) are one of the main mediators of the action of acch and their enhancement of the contractile function of the myocardium. With a critical drop in its activity in the body, the levels of acetylchamine increase and the mediation of nervous excitation completely stops.