Redlich-Flatau Disease

Redlicho-Flatau disease or syndrome.

Redlicho-flatau disease is a rare autoimmune disease that affects the central nervous system, manifesting as demyelinating multifocal encephalitis. This disease was first described by E. Redlich and E. Flatau in the 19th century.

Etymology

The name comes from the names of two Austrian psychiatrists and neurologists - Erwin Redlich (1865-1907) and Otto Flatau (1871-1922). The disease was first described as "encephalomyelitis", but after studying a large number of cases it became clear that it is not limited to the central nervous system, but can also affect the peripheral nervous system. Thus, the term was changed to Redlich-Flatau syndrome.

Pathogenesis

The pathogenesis of redlichoflatau disease is not yet fully understood. However, it is known that the body's immune system does not react adequately, which leads to the destruction of brain tissue. This may occur due to metabolic disorders in cells and damage to myelin, a fatty substance that covers nerve fibers. It is also believed that this may be due to genetic factors, namely certain mutations in genes that are involved in regulating the immune response.

Symptoms

Most often, patients with RBD suffer from traumatic brain injuries, such as concussion