Currently, the problem of the spread of HIV infection and its complications among persons in penitentiary institutions is becoming increasingly important. Despite the implementation of measures to improve the quality of inpatient treatment, the number of patients released in unsatisfactory condition is a socio-economically highly significant problem of the Federal Penitentiary Service of Russia.
One of the leading reasons for ineffective treatment in this category of care recipients is self-medication. The less information about the presence of blood diseases, which are an indication for the prescription of antiretroviral drugs and necessary for the start of treatment for the patient, the lower the quality of HIV correction for the person being released will be, especially if this is a repeated presentation. This necessitated the creation of special diagnostic standardization methods for screening among this group of convicts.
Prescribing the “necessary” antiviral immunomodulators is also an important part of preventing AIDS/HIV. Drug therapy aimed at maintaining the immunity of patients must necessarily take into account working conditions in places of deprivation of liberty, where unpredictable situations and stress loads arise that contribute to a decrease in immune defense. Therefore, there was a need to develop a new generation of combination drugs.
In addition, foreign-made drugs, which are currently provided to the Federal Penitentiary Service of Russia, are characterized by high cost and often have no less therapeutic effect than Russian drugs, which does not contribute to the wider use of the latter. This circumstance makes it important to create a Russian drug at an affordable cost that has the necessary medicinal properties, including those intended for HIV-infected patients, while the development of its analogues is also