Serology

Serology is a branch of immunology and medical microbiology that studies blood serum and its components, in particular, their role in protecting the body from infectious diseases.

Main directions of serology:

  1. Study of antibodies circulating in the blood and their interaction with antigens. This allows you to determine the presence of infection or an immune response to vaccination.

  2. Study of complement - a system of blood proteins involved in immune reactions.

  3. Analysis of other protein factors in blood plasma that play a role in immunity.

Basic methods of serology:

  1. Agglutination reaction - detection of antibodies that cause antigens to stick together.

  2. Precipitation reaction is the formation of immune complexes from antibodies and soluble antigens.

  3. The complement fixation reaction is the determination of antibodies by their ability to activate the complement cascade.

  4. Enzyme immunoassay - detection of antigen-antibody complexes using enzyme tags.

Thus, serology is a fundamental discipline that allows us to study immunity and diagnose infectious diseases based on reactions occurring in blood serum.



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What is serology? Serology is a branch of medicine that deals with the study of blood serum and their components, in particular their role in the process of protecting the body from various diseases. Serology is widely used in clinical practice to



Serological testing is the examination of animal or human blood serum for the presence of specific antibodies that help identify infection and provide information about current health status. These tests are used in human, veterinary and scientific research to detect infectious diseases, monitor the immune response to vaccinations and treat pathologies.

One of the main serological methods is the study of agglutinins, which are formed by the interaction of specific antibodies and antigens. These antigens may be microorganisms, viruses, or other disease-causing substances.

Another important serological method is complement fixation. This method involves adding complement components to the blood serum, a protein that is part of the immune system. If the serum contains antibodies, complement will bind to them, resulting in the appearance of agglutinins.