Synapse Excitatory

Excitatory synapse is a type of synapse in which depolarization of the postsynaptic membrane occurs, resulting in the generation of an excitatory postsynaptic potential. This process occurs as a result of interaction between the presynaptic terminal and the postsynaptic receptor.

An excitatory postsynaptic potential (EPSP) is an electrical signal that occurs at the postsynaptic membrane as a result of depolarization. It has a positive charge and causes an increase in the permeability of postsynaptic channels for sodium and potassium ions. This leads to an increase in the entry of these ions into the postsynaptic cell, which, in turn, leads to increased excitation.

Excitatory synapses play an important role in the transmission of information in the nervous system. They are used to transmit signals from nerve cells to muscle cells or other nerve cells. Excitatory synapses also play a role in regulating muscle tone and other physiological processes.

However, it should be noted that not all synapses are excitatory. There are also inhibitory synapses, which generate an inhibitory postsynaptic potential instead of an excitatory one. These synapses play an important role in regulating the activity of nerve cells and controlling the level of excitation in the body.

In general, the excitatory synapse is an important element of the nervous system, which plays a key role in the transmission of signals between nerve cells. Understanding its mechanisms and functions can help in the study and treatment of various diseases related to the nervous system, such as epilepsy, depression and other mental disorders.



Excitatory synapses are synapses that generate excitatory postsynaptic potentiation after the occurrence of excitation in the presynaptic term, i.e. at the end of the active transmembrane Na+ current. Excitatory postsynaptic potentials (EPSPs) and membrane potentials (Em) can be described by the following formula: Em (t + d) = Em (t) + j (Am - Ani) [8],

where j is the coefficient, Em t is the presynaptic value of the membrane potential (outside the synapse),