Conn S Syndrome

Conn's syndrome (or as described originally in 1955, hyperaldosteronism) is a condition characterized by a combination of muscle weakness, polydipsia (abnormally intense thirst), polyuria (producing large amounts of urine), and hypertension (high blood pressure) that occurs as a result of excessive secretion of the hormone aldosterone by the adrenal cortex. This hormone, which regulates sodium and potassium levels in the body, plays an important role in maintaining normal blood pressure.

Conn's syndrome is a rare disease, occurring in approximately 2% of patients diagnosed with hypertension. Most cases occur in middle age, but may appear earlier or later in life. Conn's syndrome is more often diagnosed in women than in men.

The main symptom of Conn's syndrome is hypertension, which may be difficult to control with medication. Patients may also complain of muscle weakness, muscle spasms, dry skin and mucous membranes, as well as attacks of paresthesia (numbness, tingling or burning sensations in various parts of the body). Polydipsia and polyuria that occur with Conn's syndrome are associated with excess potassium loss, which can lead to dehydration and electrolyte imbalance.

Diagnosis of Conn's syndrome involves measuring aldosterone and renin levels in the blood, as well as performing special tests such as the salt load test and the dexamethasone suppression test. Treatment may include surgical removal of the adrenal tumor, if present, or the use of drugs that block the action of aldosterone on the cells.

Overall, Conn's syndrome is a serious condition that can lead to the development of cardiovascular disease and other complications. However, modern diagnostic and treatment methods make it possible to control this pathology and prevent its complications. If you suspect Conn's syndrome, contact your doctor for further diagnosis and treatment.



Conn's syndrome (Conn S Syndrome) is a rare disease that is associated with excessive secretion of the hormone aldosterone by the adrenal cortex. This hormone is responsible for regulating sodium and potassium levels in the body. In the case of Conn's Syndrome, the level of aldosterone in the blood increases greatly, which leads to a number of characteristic symptoms.

One of the main symptoms of Conn's Syndrome is hypertension, or high blood pressure. Unlike normal hypertension due to other causes, hypertension in Conn's syndrome often does not respond to standard blood pressure medications. This can lead to serious complications such as stroke or heart attack.

Another characteristic symptom of Conn's Syndrome is polydipsia, which is an abnormally strong thirst that can lead to drinking large volumes of liquid. This, in turn, can lead to polyuria - the release of large amounts of urine.

In addition, patients with Conn's Syndrome often experience muscle weakness, fatigue, and dizziness. These symptoms are due to the fact that excess aldosterone can lead to low potassium levels in the body, which in turn can lead to impaired muscle and nervous system function.

As already mentioned, Conn's syndrome is a rare disease that occurs in approximately 2% of patients with hypertension. Diagnosis of the disease includes measuring the levels of aldosterone and renin in the blood, as well as conducting additional tests to confirm the diagnosis.

Treatment for Conn's Syndrome usually involves taking medications that block the action of aldosterone in the body, as well as adjusting potassium levels in the blood. In some cases, surgery may be necessary to remove a tumor that may be causing excess aldosterone secretion.

Overall, Conn's Syndrome is a serious condition that can lead to serious complications. However, with timely diagnosis and adequate treatment, most patients with Conn's Syndrome can achieve control over their condition and prevent the development of complications.



Conn's syndrome is a rare disease that is associated with dysfunction of the adrenal glands (endocrine glands). Excess of the hormone aldosterone causes a number of symptoms: excess fluid intake, hypertension, weight loss and muscle weakness. Today we will consider this syndrome in detail. Among the many possible causes of hypertension, only in a small number of cases can it be associated with impaired adrenal function - the hormone aldosterone, which is produced in the adrenal cortex, becomes the cause of a serious disease - Conn's syndrome. Hypertension is rarely an independent manifestation of the disease; as a rule, the function of the endocrine glands is impaired. The disease primarily affects women of reproductive age - from 30 to 50 years. Conn's syndrome presents with multiple symptoms, which are most often inconsistent and shifting. On