Splenomegaly is an increase in the size of the spleen. This condition can be caused by a number of diseases and pathological processes.
The most common causes of splenomegaly are:
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Infectious diseases such as malaria, tuberculosis, brucellosis, endocarditis. In these diseases, the spleen becomes enlarged due to the immune response to infection.
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Oncological diseases of the blood, in particular leukemia and lymphoma. Tumor cells accumulate in the spleen, enlarging it.
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Blood diseases, for example, hemolytic anemia, thalassemia. In these conditions, the spleen removes defective red blood cells, causing it to become enlarged.
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Liver diseases such as cirrhosis. With portal hypertension, blood flow to the spleen increases, causing it to enlarge.
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Infiltrative diseases, for example, amyloidosis, sarcoidosis. In these diseases, pathological proteins or granulomas are deposited in the spleen tissue.
Diagnosis of splenomegaly includes a physical examination, abdominal ultrasound, and blood test. Treatment depends on the cause and may include therapy for the underlying disease and surgical removal of the spleen.
Splenomelia is an enlarged spleen in the body, characterized by an increase in the size of the organ to a large size. Which occurs in many pathological conditions of the body. The disease splenomelia signals that the body is experiencing a malfunction of an infectious nature, an increase in infectious pathogens. Treatment for splenomelia may include both drug therapy and surgery.