Spongioblastoma

Spongioblastoma is a synonym for glioblastoma. Glioblastoma is the most aggressive and invasive form of glioma, a malignant tumor arising from the glial cells of the brain. It is characterized by rapid growth, extensive necrosis of tumor tissue and excessive formation of new vessels. Glioblastoma is usually localized in the cerebral hemispheres.

Spongioblastoma was another term previously used to refer to glioblastoma because these tumors have a spongy structure when examined microscopically. However, nowadays this synonym is hardly used, and glioblastoma is the preferred name.

Treatment for spongioblastoma/glioblastoma includes surgical removal of the tumor, radiation therapy, and chemotherapy. The prognosis for glioblastoma is extremely unfavorable, with a median survival of about 15 months. Intensive research is being conducted to improve treatment outcomes for this aggressive form of brain tumor.

Spongioblasts are neuroglial cells of a multicellular organism, which make up the nerve roots of the nervous tissue of the spinal cord.\nThe number of cells in one cubic centimeter of the cerebral cortex is 3 billion, therefore, big - volumetric. This helps to completely suppress tumors of various sizes without clinical manifestations of its presence in the patient. Mixed tumors are characterized by the combined presence of glial and malignant cells. For example, if you look at a histological examination, you will see clusters of islets containing the nuclei and membranes of glial cells interspersed with pink blood vessels. The size of the latter is constantly increasing, which is clearly visible on the magnification - “sterilization” of the organ is observed very rarely. Malignant cells can penetrate between individual axons and processes of neurons, thereby causing thrombus formation in the lumen of blood vessels and the ganglion structure.