Transamination

Transamination is one of the main reactions of amino acid metabolism in the body. Its essence is the transfer of an amino group (-NH2) from one amino acid to a keto acid to form another amino acid and a keto acid.

The reaction is catalyzed by transaminase enzymes and proceeds as follows:

Amino acid 1 + Keto acid 1 ↔ Amino acid 2 + Keto acid 2

During the reaction, an amino group is transferred from one amino acid to a keto acid due to the formation of an intermediate compound with pyridoxal phosphate (the active form of vitamin B6), which acts as a coenzyme for transaminases.

Transamination is of great importance in the metabolism of amino acids, as it allows you to convert them into each other and synthesize essential amino acids from non-essential ones. This reaction plays a key role in nitrogen metabolism and maintaining amino acid balance in the body.

Transamination is a biochemical process in which an amino group (NH2) is transferred from an amino acid to a keto acid, forming a new amino acid and a keto acid. This process plays an important role in amino acid metabolism and is necessary for protein synthesis.

Transamination occurs in cells using enzymes called transaminases. They catalyze the transfer of an amino group from an amino acid to a keto acid to form a new amino acid and a ketonic acid.

An example of transamination is the reaction between glutamic acid and α-ketoglutarate, resulting in the formation of glutamine and α-ketoglutarate. This is an important metabolic process because glutamic acid is one of the essential amino acids in proteins and α-ketoglutarate is an intermediate in the urea cycle.

For normal functioning of transaminases, coenzymes such as pyridoxal phosphate (PLP) are required to bind the amino group to the enzymatic site. Lack of PLP can lead to impaired transamination and impaired protein synthesis.

Thus, transamination plays an important role in protein synthesis and amino acid metabolism. It is carried out by transaminases and requires the presence of coenzymes such as PLP. Disruption of this process can lead to various diseases, such as amino acid deficiency or impaired protein synthesis.

Transamination, also known as transamination, is an amino acid metabolic reaction in which an amino group (NH2) is transferred from one amino acid to another. As a result, a new acid is formed - a keto acid, and the original amino acid is converted into another amino acid.

Transamination is one of the key processes in amino acid metabolism. It plays an important role in the synthesis of proteins and other important compounds in the body.

The transamination process requires an enzyme called transaminase. It catalyzes the reaction by connecting the amino group of an amino acid to the keto group of another acid. During the reaction, an amino group is transferred from an amino acid to the keto group of another acid, forming a new acid molecule and a new amino acid.