Triorthocresyl phosphate

Triorthocresyl phosphate: symptoms, consequences and treatment

Triorthocresyl phosphate (TOCP) is a highly toxic compound that has strong neurotoxic effects. This substance may cause paralytic disorders which may have serious consequences for human health.

Symptoms of intoxication can develop within 1-30 days after poisoning, with the most pronounced clinical picture appearing after 10 days. Among the first signs of intoxication may be dyspeptic disorders, dizziness and weakness.

On the 8-30th day after poisoning, peripheral spastic paralysis of the limbs may occur, which is associated with irreversible toxic damage to the spinal cord.

Treatment of TOCP poisoning should be carried out immediately and should include the following measures:

  1. Gastric lavage and use of saline laxative. These measures help quickly remove toxic substances from the body.

  2. Forced diuresis and early hemodialysis. These methods remove toxins from the blood and reduce their concentration in the body.

  3. Injections of ATP (2-3 ml of 1% solution) and proserin (2 ml of 0.05% solution) IM. These drugs can help relieve spastic paralysis and improve the general condition of the patient.

  4. Injections of thiamine (5 ml of 5% solution) intramuscularly. This drug can improve the functioning of the nervous system and reduce the toxic effects of TOCP.

In conclusion, it should be noted that TOCP is a very dangerous substance that can cause serious damage to the human body. If you suspect poisoning with this substance, you must immediately seek medical help and carry out comprehensive treatment.