Thrombus Autotoxic

What is autotoxic thrombosis?

Autotoxic thrombophlebitis is a condition in which the walls of veins and arteries are subject to the formation of blood clots (thrombi), which ultimately block blood flow in the body and lead to pain, swelling, redness and dysfunction. Typically, autotoxic thrombi occur due to the use of large amounts of blood thinning drugs, such as aspirin and warfarin, for therapeutic purposes or in connection with underlying cardiovascular diseases. These drugs act on blood clotting and decomposition, accelerating the process of blood clots. Excessive use of these drugs can lead to autotoxic thrombophlebitis, characterized by resistance to external influences and a highly aggressive course. If phlebothrombosis is detected at the initial stages of treatment, when the disease is reversible and the patient’s health is satisfactory, minimally invasive treatment methods are often used: laparoscopy, laser therapy. In advanced cases, even successful surgical treatment does not guarantee a cure. Such forms of the disease do not respond well to complex therapy or are considered an indication for limb amputation.

The cause of autotoxic thrombosis is various factors. Some of them depend on the individual and are associated with poor lifestyle and diet, others are more significant and depend on genetic predisposition. Among the factors that are associated with a person may be smoking, diabetes, obesity, consumption of alcohol and various foods, for example, unnatural fats. It is necessary to understand that the autotoxicity of thrombosis can manifest itself differently in each individual, and the reasons are sometimes unclear.