Tumor transplantation Homologous

Homologous tumor transplantation is a method of transplanting tumor cells from one organism to another genetically identical organism. The purpose of this procedure is to study the growth and development of a tumor in a new organism.

Homologous transplantation allows one to study the biological properties of tumor cells outside the donor body. Transplantation is carried out in genetically identical animals, most often laboratory mice of the same line. This avoids immune rejection of the transplant and creates optimal conditions for tumor engraftment and growth.

In the process of homologous transplantation, the tumor is removed from the donor animal, crushed and injected into the recipient. The growth of the transplanted tumor is carefully observed and recorded. The growth rate, metastasis, and histological picture are analyzed.

The homology model is widely used in oncology research to study the mechanisms of tumor growth, test anticancer drugs, and develop methods for diagnosing and treating malignant neoplasms.