Two septol

Country of origin - Russia
Pharm-Group - Combined antimicrobial agents

Manufacturers - Shchelkovo Vitamin Plant (Russia)
International name - Co-trimoxazole
Synonyms - Apo-Sulfatrim, Baktekod, Baktoreduct, Bactrim, Bactrim forte, Berlocid, Berlocid 240, Berlocid 480, Berlocid 960, Bi-Septin, Bikotrim, Biseptol, Biseptol 480, Bisutrim, Brifeseptol, Gen-Ultrazol, Groseptol, Disepton, Duo -Septol, Intrim, Co-trimoxazole, etc.
Dosage forms - tablets 480 mg, tablets 120 mg
Composition - Sulfamethoxazole + Trimethoprim

Indications for use:

1. Respiratory tract infections (bronchitis, pneumonia, pleural empyema, etc.)
2. Urinary tract infections (cystitis, pyelonephritis, etc.)
3. Urogenital infections (gonorrhea, chancroid, etc.)
4. Gastrointestinal infections (diarrhea, typhoid fever, cholecystitis, etc.)
5. Skin and soft tissue infections (furunculosis, abscesses, etc.)
6. Infections of the ENT organs (otitis media, sinusitis, laryngitis)
7. A number of severe infections (sepsis, meningitis, osteomyelitis, etc.)

Contraindications:

1. Hypersensitivity to the components of the drug
2. Liver and kidney diseases
3. Enzyme deficiency
4. Pregnancy and breastfeeding
5. Children up to 2 months (oral administration)
6. Children under 6 years of age (parenteral administration)

Side effects:

1. Dyspepsia, hepatitis, pancreatitis
2. Agranulocytosis, anemia, thrombocytopenia
3. Nephrotoxicity, crystalluria
4. Allergic reactions
5. Headache, peripheral neuritis

Special instructions:

1. Dose adjustment for renal impairment
2. Monitoring blood composition and liver/kidney function during long-term use
3. With caution in patients with folic acid deficiency, allergies, asthma
4. Stop taking if allergic reactions occur
5. Avoid use for infections caused by group A streptococcus

Literature:
Encyclopedia of Medicines, 2004.