Uric acid

Uric Acid: Role and Pathological Conditions

Uric acid (Uk) is the end product of purine metabolism in the human body. Chemically, it is 2,6,8-trioxypurine. M. has an important physiological role, but increased concentrations of this substance in the blood may be associated with various pathological conditions.

Purine metabolism is an important biochemical process in the body, which results in the formation of uric acid and other compounds. Purine bases, such as adenine and guanine, are present in nucleic acids (DNA and RNA) and are necessary for protein synthesis and some metabolic processes.

Uric acid is formed as a result of the destruction of purine bases. It usually dissolves in the blood and is excreted through the kidneys in the urine. However, some diseases and metabolic disorders can lead to increased levels of M. in the blood, which can have serious health consequences.

One of the common diseases associated with high uric acid levels is gout.

Uric acid (UA) is the end product of purine metabolism in the body's cells. It is an important component of the uric acid processing process that occurs in the kidney and liver. Uric acid is excreted from the body through urine and feces, and its concentration in the blood can vary depending on the level of purine metabolism.

Uric acid is formed from purine, which is found in foods such as meat, fish, legumes and grains. Purine goes through a process of dehydration and hydrolysis, where it is broken down into uric acid and ammonia. After this, uric acid is excreted through the kidneys and converted into nitric acid in acid-base balance.

However, the concentration of uric acid in the blood can also increase in some diseases. For example, in gout, which occurs due to the accumulation of uric acid in the extracellular fluid, the level of M.C. in blood plasma increases. Also, an increase in the concentration of M. C. can be observed in many kidney diseases, when the rate of excretion of uric acid slows down, including nephritis.

It is important to note that uric acid is one of the important indicators of metabolism and functioning of the human body. Its plasma level can indicate the presence of various diseases and conditions, such as nephritis, diseases associated with high levels of uric acid (for example, gout), kidney disease, inflammation and injury.

One of the reasons for the increase in the level of M. C in the blood is a violation of urination, when the kidneys cannot remove uric acid effectively enough. If the kidneys cannot cope with the removal of M.K., it accumulates in the tissues and causes high levels and increase in blood pressure, which is dangerous to health. In addition, elevated uric acid can lead to arterial damage, arteriosclerosis, and even heart attack.

Overall, uric acid plays an important role in the metabolism and functioning of the body. Its plasma concentration needs to be monitored to evaluate a number of different diseases, including gout and kidney disease. Therefore, regular testing of uric acid levels can help prevent various diseases and maintain kidney health for a longer period of time.