Vancolled

Vancoled (international name - vancomycin) is an antibiotic produced by Waeth-Lederle in the United States of America. This drug belongs to the group of antibiotics of different classes and is used for the treatment of severe infectious and inflammatory diseases caused by pathogens sensitive to vancomycin, with the ineffectiveness and intolerance of penicillins, cephalosporins and other antibiotics.

Vancoled is available in the form of a lyophilized powder for the preparation of an injection solution in dosages of 500 mg and 1000 mg. The active ingredient of the drug is vancomycin.

Indications for the use of Vancoled include severe infectious and inflammatory diseases such as sepsis, endocarditis, pneumonia, lung abscess, osteomyelitis, infections of the skin and skin structures, pseudomembranous colitis caused by Clostridium difficile, enterocolitis and meningitis.

Contraindications to the use of Vancoled include hypersensitivity to the drug, acoustic neuritis and pregnancy in the first trimester. This drug also has restrictions for use in severe kidney damage, hearing impairment, pregnancy in the second and third trimesters, and during breastfeeding (breastfeeding should be stopped).

Vancoled may cause side effects such as nausea, vomiting, bitter taste in the mouth, chills, itchy skin, hives, and Stevens-Johnson syndrome. After IV administration, thrombophlebitis, vasculitis, fever, neutropenia, eosinophilia, thrombocytopenia and sometimes anaphylactoid reactions may occur. With rapid intravenous administration, a burning sensation, redness of the upper body (red neck syndrome), pain and muscle spasms in the back and chest, arterial hypotension, dizziness, and tinnitus are possible. In rare cases, oto- and nephrotoxic reactions may be observed (hearing loss up to deafness, renal failure, azotemia, interstitial nephritis).

Interaction of Vancoled with other drugs can lead to hearing loss and kidney damage. Concomitant use with general anesthetics can lead to the development of erythema, histamine-like reactions and arterial hypotension. In addition, Vancoled can enhance the effect of muscle relaxants and anticoagulants.

The dosage and duration of taking Vancoled depend on the severity of the infectious process, age, weight and functional state of the patient. Usually the drug is used as an intravenous infusion of 1 g 2 times a day with an interval of 12 hours. The duration of treatment can vary from 7 to 10 days or more depending on the clinical picture and the effectiveness of therapy.

Vancoled is a powerful antibiotic and should only be used as prescribed by a doctor. Self-medication and improper use of the drug can lead to the development of pathogen resistance, increasing the risk of complications and unwanted side effects. If any symptoms or side effects occur, you should contact your doctor immediately.