Ventax

Ventax: use, side effects and special instructions

Ventax (international name - Theophylline) is a bronchodilator from the group of phosphodiesterase inhibitors. The drug is manufactured in the Netherlands by Yamanouchi Europe B.V. and is used for the treatment of bronchial asthma, status asthmaticus, obstructive bronchitis, emphysema and apnea in newborns (adjuvant).

Ventax is available in the form of extended-release capsules in various dosages - 100 mg, 200 mg and 300 mg. The active substance is theophylline.

Despite the effectiveness of the drug in the treatment of respiratory diseases, it has a number of side effects. Some may be serious and require medical attention. These include anxiety, impaired consciousness, convulsions, visual disturbances, angina attacks, arrhythmias, tachycardia, hypotension, laryngitis, sore throat, flu-like syndrome, nasal congestion, xerostomia, anorexia, nausea, vomiting, heartburn, exacerbation of cholecystitis, cholestatic hepatitis, increased concentrations of liver enzymes (AST, ALT, alkaline phosphatase, LDH), intestinal atony, leukopenia, hypofibrinogenemia, pancytopenia, thrombocytopenia and allergic reactions.

Ventax may also interact with other medications. For example, cimetidine, allopurinol, cyclosporine A, macrolide antibiotics, oral contraceptives, and influenza serum may reduce clearance and increase the risk of side effects. Phenobarbital, phenytoin, xanthines and smoking, on the contrary, can accelerate biotransformation. Beta blockers reduce bronchodilator activity. Adsorbents, coating agents, antacids and oxidizing agents slow down absorption and reduce Cmax, while alkalizing substances increase it. Enhances the effects of diuretics, reduces NSAIDs (from the group of pyrazolone derivatives), beta-blockers, probenecid.

If you suspect an overdose of Ventax, you should consult a doctor. Symptoms of overdose may include agitation, confusion, seizures, tachycardia, arrhythmia, hypotension, nausea, vomiting, hypokalemia, hypoxia, hyperglycemia, and fever. Treatment of overdose includes immediate discontinuation of Ventax, symptomatic treatment and administration of activated charcoal.

It is important to note that Ventax should not be prescribed to patients with gastric and duodenal ulcers, severe cardiac damage, severe liver and kidney dysfunction, hyperthyroidism, epilepsy, neuroses, rheumatic diseases, glaucoma, bronchial asthma with severe hypoxia and a history of therapeutic doses of theophylline .

You should also be careful when prescribing Ventax to elderly patients, pregnant and lactating women, children and patients with electrolyte imbalance, thyrotoxicosis, arterial hypertension, coronary insufficiency, arrhythmia, chronic obstructive pulmonary disease.

Before you start taking Ventax, you must consult your doctor and strictly follow the dosage and regimen of taking the drug.