Weyl-Felix Reaction

The Weyl-Felix reaction (also known as the Weyl-Weyl reaction) is one of the methods for determining enzyme activity in biochemical studies. This method was developed by Czech bacteriologist Alexander Felix and Austrian microbiologist Erich Weyl in 1913.

The basic idea of ​​the Weyl-Felix reaction is that an enzyme that catalyzes a particular reaction can be used to convert one substrate into another substrate. During the reaction, a product is formed that can be determined using special methods.

To carry out the Weyl-Felix reaction, it is necessary to add a substrate to the enzyme and observe the change in its concentration over time. If the enzyme activity is high, the concentration of the product will increase faster than in the case of low activity.

The Weyl-Felix reaction is one of the most common methods for determining enzyme activity in biochemistry. It allows you to quickly and accurately determine enzyme activity, which is especially important for scientific research and the development of new drugs.

The Weyl-Felix reaction is a chemical process that occurs when two different substances interact. In this case we are talking about the reaction of two organic substances - felix and weil. Initially, the reaction was named after its discoverer, Felix Weyl, who was an Austrian microbiologist. However, he later became known as Avram Geller (also known as Abram Felixa von Weiler), and this reaction began to be called by his name.

The discovery of the reaction is associated with the research of F. Weil and F. Abel (Austrian chemist, also one of the discoverers of lactone) in the middle of the 20th century. The scientists' work was based on the idea that some organic substances can participate in biosets (sets of biologically active compounds). Research has shown that most organic substances, even those not connected to each other, can form various biomolecular bonds. At