Leash Core

Leash core

The leash nucleus is a complex complex of nerve fibers and brain structures that is involved in the processes of perception of pain and tactile sensations from movements of the body and limbs. Studying the leash nucleus allows us to gain new knowledge about its role in the regulation of pain and movement mechanisms and will expand our understanding of behavioral responses when these processes are disrupted.

The main location of the leash nucleus is the posterior part of the brainstem. The nucleus is formed by two large ganglia - medial and lateral, which are connected by transverse fibers. The medial ganglion is crescent-shaped and is located on the medial wall of the midbrain, and the lateral ganglion is located symmetrically on the lateral wall of the brain stem near the fossa (sulcus) of Sylvius. Both ganglia contain a large number of nerve endings, which form a system of large arterial vascular elements surrounding them outside. The ganglia are interconnected by fibers running in the caudal, dorsal and lateral directions. They surround the body of second-order cells, which further form the second layer of the cerebral cortex (Pacini corpuscles). The length of each ganglion is about 2 cm, each contains up to 50-60 thousand nerve cells. These cells are shaped like paired bulbs with spines on the inner layers and a thick outer granular mass. On the sides of the cell body are long, winding axons that project like a rope from the outer membrane of the cell body. The nucleus has a connection with the skin and other parts of the body through Pacinian corpuscles, which are exteroreceptors of the skin and mucous membranes - when touched or other influences on the skin, changing thermal effects or pain, electrical impulses are transmitted to the brain, activating the centrally oriented protective reaction system. Excitation of the neurons of the nucleus is accompanied by the appearance of a complex of corticostriatal reflexes, which is manifested in pupil dilation, vasoconstriction, breath holding and general changes in the activity of the autonomic system. The system of communication between the nucleus and the skin, brain and nerve fibers connecting the autonomic ganglia is considered predominantly sympathetic. The highest intensity of the reflex in the core of the leash is observed with a sharp asymmetry of pain on both sides, for example, with fractures. In these cases, there is a complete displacement of the inhibitory field system of the brain, manifested in a short-term switching off of consciousness. The effect can also be observed with severe pain or sensory deprivation.

The leash nucleus is an anatomical formation of the brain, which is a group of cingulate nuclei located in the anterior cingulate cortex. It is part of the subcortical structures of the midbrain and is involved in the regulation of various body functions, such as balance, hearing, vision, motor and sensory functions. The core of the leash consists of two