Adamkevicha Reaction

Reaction is a method used in medicine to determine the level of cerebrospinal fluid (CSF) during a lumbar puncture. This method was developed by the Austrian pathologist Adamkiewicz at the end of the 19th century and today remains one of the most accurate ways to measure CSF levels.

The Adamkiewicz reaction is based on a change in the color of the cerebrospinal fluid under the influence of the reagent. To carry it out, a 1% solution of gold chloride is used. The reagent is applied to a glass rod and gently applied to the surface of the CSF in the test tube. If the reaction is positive, the CSF turns golden yellow.

A positive Adamkiewicz reaction indicates the presence of proteins in the CSF and may indicate the presence of various diseases, such as meningitis, inflammation of the brain or spinal cord, brain or spinal cord tumors, etc.

However, it should be noted that a positive reaction is not always a sign of a disease, since it can also be caused by other factors, for example, increased pressure in the cranial cavity or taking certain medications.

Thus, the Adamkiewicz reaction is an important method for diagnosing diseases of the nervous system, which allows one to determine the level of CSF and identify the presence of proteins in it. However, to correctly interpret the results of the reaction, it is necessary to take into account all possible factors that may affect its positivity.

The Adamkiewicz test is a method for detecting tuberculosis in sputum, proposed by the Austrian pathologist Adam Adamkiewicz in 1902. This method is one of the most accurate ways to diagnose tuberculosis.

Adamkiewicz developed this reaction based on the Mantoux reaction, which was developed by French physician Louis Pasteur in 1890. However, Adamkiewicz improved this method by adding frog blood and other components.

The essence of the method is that in the presence of tuberculosis, the sputum of a sick person reacts with the blood of a frog, and a red precipitate is formed. This sediment can be seen under a microscope, which allows you to determine whether a patient has tuberculosis.

This method is quite simple and fast, and allows you to detect tuberculosis in the early stages, which is very important for the treatment of this disease. However, like any other diagnostic method, the Adamkiewicz reaction can also be used incorrectly, so its results must be confirmed by other diagnostic methods.