Afzelius-Lipschütz Chronic Migratory Erythema

Afzelius-Lipschutz chronic migratory erythema is a rare skin disease that is characterized by the development of clear round spots with well-defined borders. This is a chronic (long-term), migratory (moving place of appearance) skin lesion. The appearance of the spot appears in the form of a large circle, which gradually enlarges, a small navel appears, surrounding it with a reddish-brown rim. Over time, the belly button may disappear, but the spot will slowly begin to resemble a round button filled with a red-brown substance. The spots may be itchy, irritating, or painful. Treatment of the condition involves the use of local agents to reduce inflammation and regenerative properties. The condition may progress and require professional medical attention to determine the best treatment approach.



Afzelius-Lipstutz chronic migratory erythema is a rare dermatological disease that appears as a reddish rash on the skin. This disease was described by Dr. A. Afzelius and Associate Professor W. Lipschutz in 1904.

Afzelius was a Swedish dermatologist and Lipschutz was an Austrian dermatologist. They both believed that chronic migratory erythema was a specific condition that was characterized by cyclical bouts of skin rashes that moved along the body.

Symptoms of the disease may include:

* redness, peeling and itchy lesions on the skin; * redness of the feet and palms; * exacerbation of symptoms after physical activity; * pain in the chest and abdomen.

Usually, several months pass from the appearance of the first symptoms before it becomes possible to diagnose the disease. However, the disease is completely reversible and symptoms subside within a few weeks after



Afzelius-Lipschütz syndrome

**Synonyms:** Erythema of Afzelius-Lipshutz, Periosteal bone of Afzelius Lipsutzer, Erythematous tumor of Afzelius-Lipschutz, Afzelius-Lipshtokussevach disease. In the 20th century, it was isolated by the Swedish dermatologist Jacob Afzelius and his Austrian colleague Wilhelm Lipschutz.

Etiology

There are several versions of the etiology of the disease:

- Disorders of the autonomic nervous system in the forearm; - Biological factors; - Physical effects on the walls of blood vessels.

The disease was originally called “marginal migratory erythematous dermatitis.” Later, under the name “Lipshaw syndrome,” the disease was described by a British neurologist. The most correct and logical for today