Alkylating Agents

Alkylating Agents are a class of drugs used in chemotherapy to treat various types of cancer. These drugs exert their therapeutic effect by binding to the DNA of cells and changing its structure, which leads to disruption of the process of cell division and their death.

The principle of alkylating agents is that they add an alkyl group to specific atoms in the DNA molecule. This leads to a change in the DNA structure and disruption of the process of copying genetic information during cell division. As a result, cells cannot continue their life cycle and begin to die.

There are many different alkylating agents that are used in medicine. Some of them include cyclophosphamide, melphalan, chlorambucil, cycloserine, buzulfan and others.

Cyclophosphamide is one of the most widely used alkylating agents in medicine. It is used to treat various types of cancer, including lymphoma, leukemia, bladder cancer, ovarian cancer and others. This drug is introduced into the body by injection or intravenous drip.

Melphalan is another alkylating agent that is used to treat cancer. It is often used to treat multiple myeloma (bone marrow cancer) and other types of cancer. This drug is usually taken in tablet form.

Chlorambucil is an alkylating agent that is used to treat various types of blood cancers, including lymphoma and leukemia. This drug is taken in tablet form.

Cycloserine and buzulfan are other alkylating agents that are used medically to treat various types of cancer. They are introduced into the body in the form of injections or intravenous drips.

Although alkylating agents can be effective in treating cancer, they can also cause side effects. Some of the possible side effects include nausea, vomiting, hair loss, fatigue, increased chance of infection, and others. Therefore, it is necessary to carefully evaluate the benefits and possible risks of using these drugs.

In conclusion, alkylating agents are an important class of drugs used in chemotherapy to treat cancer. They exert their therapeutic effect by binding to the DNA of cells and changing its structure, which leads to disruption of the process of cell division and their death. Despite possible side effects, these drugs can be effective in treating cancer and play an important role in modern medicine. However, as with any treatment, it is important to carefully evaluate the benefits and possible risks of using alkylating agents.



Alkylating comes from the Greek "alkalio" - lye, and "philotheos" - the sphere of the divine. One such class of drugs in this therapy are alkylating agents. The components of alkenes differ in their mechanism of action and purpose. How do they affect the body? Roughly speaking, the mechanism of action of the agents is based on the inactivation of cell DNA and all genome restoration mechanisms. It is due to this that it is possible to achieve maximum effectiveness in cancer therapy. The prescription of alkiline is based on individual indications for patients.



Alkylation agents, or, as they are also called, conjugation agents, are used for antitumor treatment of malignant tumors in cancer patients.

The mechanism of action on cells is associated with a direct effect on the DNA chain. The first to discover this was the Soviet