Akriderm Gk

Manufacturer country

Russia

Pharm Group

Combined products containing glucocorticosteroids

Manufacturers

Akrikhin HFC (Russia)

International name

Gentamicin+Betamethasone+Clotrimazole

Synonyms

Triderm

Dosage forms

cream

Compound

Active ingredient: Betamethasone dipropionate, gentamicin sulfate, clotrimazole.

Indications for use

Dermatoses complicated by primary and secondary infection, in the treatment of athlete's foot, pityriasis versicolor, dermatomycosis (including inguinal) caused by pathogens sensitive to the drug.

Contraindications

Hypersensitivity to any of the components of the drug. skin tuberculosis, skin reactions after vaccination, chicken pox, skin manifestations of syphilis, diabetes mellitus, glaucoma, pregnancy, breastfeeding, children under 7 years of age.

Side effect

Local reactions: burning sensation, erythema, exudation, pigmentation disorders, itching. Adverse reactions caused by betamethasone: burning sensation, itching, irritation and dry skin, folliculitis, hypertrichosis, acne-like rashes, hypopigmentation, perioral dermatitis, skin maceration, secondary infection, atrophy skin, stretch marks, prickly heat. Adverse reactions caused by clotrimazole: erythema, peeling, local swelling, itching, urticaria, skin maceration, paresthesia. Adverse reactions caused by gentamicin: hyperemia, itching.

Interaction

No data.

Overdose

Symptoms: if doses are exceeded: weight gain, edema, hypertension, glucosuria, hypokalemia. Treatment: symptomatic.

special instructions

Cannot be used in ophthalmic practice. Any side effects encountered with the use of systemic glucocorticosteroids, including suppression of adrenal cortex function, may also be observed with topical use of glucocorticosteroids, especially in children. Systemic absorption of glucocorticosteroids or gentamicin when applied topically will be higher if treatment is carried out on large surfaces of the body or when using occlusive dressings. Avoid applying gentamicin to open wounds or broken skin. Appropriate precautions should be taken in such cases, especially when treating children. It is recommended to discontinue the drug after long-term use gradually. When used, like many other topical glucocorticosteroids, on large surfaces and/or with an occlusive dressing, suppression of the function of the hypothalamic-pituitary-adrenal system is possible , there may be a decrease in growth hormone excretion, as well as an increase in intracranial pressure.

Literature

Encyclopedia of Medicines 2004