Alpha Adrenergic Blocking Agents

[Article title: "Alpha-Adrenergic blocking agents" - abroad"](

**Alpha-adrenergic blockers**, see non-α-adrenergic blockers, are a pharmacological group of drugs that have a moderate or strong stimulating effect on postsynaptic adrenergic receptors of the α2 subtype in peripheral tissues. This increases blood pressure, but reduces sympathetic activity, blood circulation, dilates blood vessels and can increase the production of dopamine and serotonin. Drugs in this group are widely used to treat depression, hypertension, and are also used to reduce symptoms of alcohol and drug withdrawal. Used for diabetes and hyperthyroidism. Some antihistamines (diphenhydramine) have some alpha-adrenergic blocking effect. By changing the activity of alpha adrenergic receptors, the intensity of pain can be reduced. There are several groups of alpha adrenergic blockers: centrally acting blockers (central), sedative blockers, sympathomimetic blockers and Alpha-2 blockers.