Alkaline Blood Reserve

Alkaline blood reserve: functionality of the buffer system

The alkaline reserve of the blood is an important indicator of the functional capabilities of the body's buffer system. It represents the amount of carbon dioxide that can be bound by 100 ml of blood plasma, previously brought into equilibrium with a gaseous environment in which the partial pressure of carbon dioxide is 40 mmHg.

The blood buffer system plays a key role in maintaining the acid-base balance of the body. The body needs to maintain optimal blood pH levels to ensure normal functioning of cells and tissues. Acid-base balance is controlled by various buffer systems, including the blood, lung and kidney systems.

The alkaline reserve of the blood is one of the indicators that allows us to assess the ability of the blood buffer system to compensate for changes in pH. It reflects the amount of bases (alkaline substances) in the blood, which can bind excess acids and help maintain normal pH.

Measuring the alkaline reserve of the blood is carried out by bringing the blood plasma into contact with a gaseous environment containing a certain partial pressure of carbon dioxide. When this occurs, excess carbon dioxide reacts with bases in the blood to form bicarbonate and other alkaline compounds. Alkaline reserve is expressed in milliliters of carbon dioxide bound to 100 ml of blood plasma.

The normal blood alkaline reserve value is usually 22 to 28 millimolar equivalents per liter. Changes in this indicator may indicate acid-base imbalance, such as metabolic acidosis or alkalosis.

Metabolic acidosis is characterized by a decrease in the alkaline reserve of the blood, which can be caused by a variety of reasons, including kidney disease, diabetes, fasting, or the use of certain medications. In metabolic acidosis, the body has difficulty maintaining a normal blood pH, which can lead to a variety of symptoms and complications.

On the other hand, metabolic alkalosis is characterized by an increased alkaline reserve of the blood. This may be due to certain conditions, such as vomiting, certain medications, or kidney problems. Increased alkaline reserve can lead to a shift in blood pH towards the alkaline side, which can also cause various symptoms and problems.

Assessing the alkaline reserve of the blood is an important tool for diagnosing and monitoring the acid-base balance of the body. Doctors can use this indicator in combination with other clinical data to determine the causes and nature of acid-base imbalance and develop appropriate treatment.

In conclusion, the alkaline reserve of the blood is an indicator of the functionality of the body's buffer system. It reflects the blood's ability to compensate for changes in pH by binding excess acids. Measuring the blood alkaline reserve is an important tool for diagnosing and monitoring acid-base imbalances. Understanding this indicator will help doctors identify disorders and develop appropriate treatment aimed at restoring normal acid-base balance in the body.



Alkaline blood reserve (ABR) is an indicator of the functional capabilities of the blood buffer system. This is the amount of carbon dioxide that can be bound to 100 milliliters of blood plasma, provided that it is in equilibrium with the gaseous environment and the partial pressure of CO2 is 40 millimeters of mercury (mmHg).

Alkaline reserve reflects the blood's ability to bind carbon dioxide, which is an important indicator of homeostasis. It can vary depending on various factors such as age, gender, level of physical activity, diet and others.

Normally, the alkaline reserve should be in the range of 30 to 50 milliliters. However, if this indicator is below normal, then this may indicate the presence of various diseases, such as anemia, kidney or liver disease, as well as disturbances in the functioning of the buffer system.

Measuring the alkaline reserve of the blood is an important diagnostic test when assessing health status. In addition, this test can be used to monitor the effectiveness of treatments for various diseases.

Thus, the alkaline reserve of the blood is an important indicator of the functionality of the buffer system and can be used for the diagnosis and monitoring of various diseases.