Allergic Reaction Cross

Allergic Cross Reaction: Understanding and Treatment

An allergy is a reaction of the immune system to normally harmless substances such as pollens, foods, pets and other allergens. However, sometimes the immune system can confuse these substances with something more dangerous, leading to an allergic reaction. A cross-reactive allergy is a type of allergic reaction that can occur when the immune system reacts to cross-reacting antigens.

Cross-reacting antigens are common components that are present in different allergens. For example, proteins found in pollen from different plants may share epitopes (certain parts of protein molecules) that cause an allergic reaction in some people. Thus, if a person is allergic to one type of plant, he or she may have an allergic reaction to another type of plant that contains cross-reactive antigens.

A cross allergic reaction can manifest itself in different forms. For example, a person may experience allergic rhinitis (runny nose) when they inhale pollen from certain plants, but may also experience an allergic reaction to foods containing cross-reacting antigens. In addition, a cross-allergic reaction can be more severe, for example, anaphylactic shock, which is a life-threatening condition.

To diagnose a cross-reacting allergy, it is important to perform allergen tests to determine which cross-reacting antigens a person may be reacting to. This may help identify other allergens that may be causing a similar reaction and provide an opportunity to eliminate them.

Treatment for an allergic cross-reaction may include the use of antihistamines, which reduce allergy symptoms such as itching, runny nose, and red eyes. In more severe cases, the use of corticosteroids or epinephrine may be required. It is also important to avoid contact with allergens to prevent a recurrence of the reaction.

In conclusion, allergic cross-reaction is an important aspect of allergies that can lead to various symptoms and even life-threatening conditions. Understanding cross-allergy and its relationship to cross-reacting antigens can aid in the diagnosis and treatment of allergic reactions. If you suspect a cross allergic reaction, it is important to consult an allergist who will conduct the necessary tests and select an effective treatment. Also, avoid exposure to allergens to prevent a recurrence of the reaction and improve your health.

A cross-type allergic reaction is an allergic reaction that is caused not by the substance itself, but by its co-antigens, which may be similar in structure and location and located in another substance, but belong to a different class of heterogeneity.

Causes of occurrence The cause of A.R.P. are HLA class II genes, encoding proteins of the major histocompatibility complex class II, which contains known membrane structures: B2 marker, B7 membrane antigen, a2.43 antibody and B15 antigen. If the genotype contains HLA I and HLA II classes, a reaction to substances from other classes is possible and is cross-reactive. An associative character is often observed between the dominant position of the HLA 1QA gene, characteristic of certain ethnic groups, and the HLA 2DQw6, HLA 5DP11 and HLA DR2 genes, since previous studies have been done that the frequency of their occurrence in the homozygous state is observed to a much greater extent. For example, in the German ethnic group, the frequency of heterozygotes for HLA 1qA*0201, HLA2 DQw6 and HLA 3DP*11 is 90%. The most common alleles of the recoded gene in heterozygous individuals are HLA 2DR*09, HLA DR 4DQ8, HLA 5DP*87619.080, HLA1 Q*0702, HLA10 Q*0605, HLA B16, 3DQ7, HLA DPB1*21391. The presence of multiple allergies may be associated with severity course of the disease, some patients have complications from it. Allergies are multifactorial, so genetics ranks high among the causes of allergic reactions. For example, studies show that in the presence of HLA class III genes, severe forms of obstructive asthma, bronchial asthma in children, atopic dermatitis, eczema, and urticaria in adults are more common. Other factors are drug, food, seasonal allergies, and the presence of allergic children in the family. In the general population, the prevalence of such diseases ranges from 6.2 to 41.2%, the highest percentage is represented in the Middle East - over 40%, in Asia - 23.4-39%, in Europe - from 8 to 20%.