Allergoid Reaction

Allergoid reactions are allergic reactions of the second type (phototoxic), caused by substances that are irritating in high concentrations (aldehydes with divalent metals, halogens, heavy metals, phenols and their reduction products). Acute toxicoallergic inflammation of the skin is characteristic. Clinically, with the cutaneous route of administration, it is cyanosis, puffiness of the face and neck, a metallic taste in the mouth and often vomiting, painful itching in all parts of the body (less often, only a limited area is affected - the “place of deposition”). Among the possible causes of NRC, see Viral encephalitis. Allergoids are anthrax rashes, accompanied by local and general allergic reactions, skin tuberculosis, poisoning with mercury, silver, copper, nickel salts, as well as pseudotuberculosis. The diagnostic criterion in favor of an allergoid reaction is: an increase in allergic symptoms in the event of repeated administration of the allergen; absence of hyperemia and edema. The severity of allergoid reactions can vary from generalized urticaria to anaphylactic shock. The clinical manifestations of allergic dermatitis resemble scabies. Patients complain of severe skin itching.