Allopurinol

Allopurinol is a drug that is widely used to treat chronic gout. This disease is associated with increased levels of uric acid in the blood and tissues of the body, which leads to the formation of uric acid crystals in the joints and kidneys. Allopurinol helps lower uric acid levels in the body, preventing the formation of crystals and the development of gout.

Allopurinol is part of a group of inhibitors of xanthine oxidase, an enzyme that is involved in the formation of uric acid. The drug blocks the action of this enzyme, which leads to a decrease in the level of uric acid in the blood and tissues of the body.

The drug is usually taken orally, after meals, with plenty of water. The dosage depends on the severity of the disease and the patient's condition, and can be changed by the doctor depending on the effectiveness of treatment and side effects. Usually the initial dose is 100-300 mg per day, which is gradually increased to the desired level. The maximum dose is 800 mg per day.

Allopurinol may cause a number of side effects, including nausea, vomiting, diarrhea, headache, fever, stomach pain and skin rash. In rare cases, the drug can cause damage to the nervous system and enlargement of the liver. If any unwanted effects occur, you should consult a doctor.

Allopurinol is available under various trade names, including Hamarin and Zyloric. The medicine is a prescription drug and can only be dispensed with a doctor's prescription.

In conclusion, allopurinol is an effective drug for the treatment of chronic gout. However, like any medicine, it can cause unwanted effects, so it must be taken strictly as prescribed by a doctor and under his supervision.

Allopurinol is a drug for the treatment of chronic gout that helps reduce uric acid levels in body tissues. It is taken orally and can cause various side effects such as nausea, vomiting, diarrhea, headache, fever, stomach pain and skin flushing.

In rare cases, allopurinol can cause damage to the nervous system or enlargement of the liver. However, with proper use and dosage, allopurinol is an effective drug for the treatment of chronic gout.

Trade names for allopurinol include gamarin and cyloric. It is important to remember that allopurinol must be prescribed by a doctor and should only be taken as prescribed by a specialist.

Name of the drug: Allopurilan Release form: Tablets and capsules Indications for use: Treatment of chronic gout complicated by impaired purine metabolism. Rarely used as a lipid-lowering agent. Contraindications: Any form of allergy reactions to purine derivatives (polyuria, pyuria), pathology of the hematopoietic system and blood vessels, severe hepatic and renal metabolism. Method of administration and dosage: Treatment should begin with 300-400 mg/day, followed by a dose reduction of 250-500 mg every 7 days. The dose is set individually, taking into account the clinical effectiveness and tolerability of the drug. The optimal maintenance dose is 150-300 mg/day. The recommended duration of treatment is 6-12 months. Long-term use of the drug is possible (for 1 year) under the control of purine and lipid metabolism, as well as indicators of the activity of enzymes involved in their metabolism. While taking allopurilan, the intake of sodium, phosphorus and potassium salts from food should be limited. The presence of concomitant diseases, lifestyle, and intake of nutritional supplements may affect purine requirements, and therefore it is recommended to consult with your doctor before starting therapy. When used simultaneously with thiazide diuretics, it is possible to reduce the level of uric acid in the blood and urine; with digoxin, probenecid, NSAIDs - an increase in the concentration of the latter in the blood serum;