Amphotericin

Amphotericin B is an antibiotic produced by Streptomyces nodosus and is active against many parasitic fungi, including fungi that cause infections in humans. It is used medicinally to treat fungal infections such as mucormycosis, aspergillosis and cryptococcosis.

Amphotericin B is a polypeptide antibiotic consisting of two different components: amphotericin B1 and amphotericin B2. These components have different properties and act on different targets in the fungal cell. Amphotercine B1 inhibits fungal growth, and amphotercine B2 destroys fungal cell walls.

To treat fungal infections, amphotericin is administered intravenously or intramuscularly. The dose is determined individually depending on the severity of the infection and the patient's condition.

However, the use of amphotericin may cause side effects such as nausea, vomiting, diarrhea, muscle cramps and kidney problems. Therefore, treatment with amphotericin should only be carried out under medical supervision.

Overall, amphotericin is an important drug for the treatment of fungal infections. However, its use should be limited and under the supervision of a physician.