Amoxiclav

The activity of amoxiclav may decrease when taken simultaneously with antacids that contain aluminum and magnesium, as well as with drugs that reduce the acidity of gastric juice.

Amoxiclav is a combined antimicrobial agent that contains amoxicillin and clavulanic acid. Amoxicillin is an antibiotic of the penicillin group that has a broad spectrum of action against many bacteria, including gram-negative ones. Clavulanic acid is a beta-lactamase inhibitor that prevents bacterial enzymes from breaking down amoxicillin.

Amoxiclav is widely used to treat infectious diseases caused by microorganisms sensitive to its action. It is effective in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, biliary tract infections, bone and connective tissue infections, skin and soft tissue infections, as well as odontogenic and sexually transmitted infections.

Like any other medicine, amoxiclav can cause side effects. They most often manifest themselves in the digestive system, such as loss of appetite, nausea, vomiting and diarrhea. In rare cases, allergic reactions such as itching, skin rashes, angioedema, bronchospasm and anaphylactic shock may occur. It is also possible to develop pseudomembranous colitis with severe diarrhea.

When using amoxiclav, it is necessary to take into account its interaction with other drugs. For example, when taken simultaneously with methotrexate, the toxicity of methotrexate increases, and when used with allopurinol, the incidence of exanthema increases. Amoxiclav may also reduce the effectiveness of oral contraceptives.

In general, amoxiclav is an effective and widely used antimicrobial agent for the treatment of various infectious diseases. However, before using it, you must consult your doctor and take into account all contraindications and possible side effects.