Angiotensin (Angiolensin)

Angiotensin is one of two peptides: angiotensin I or angiotensin II.

Angiotensin I is produced in the liver from a protein (alpha globulin) under the influence of renin formed in the kidneys, from where it enters the blood. When blood passes through a person's lungs, an enzyme converts angiotensin I into angiotensin II.

This peptide causes blood vessels to constrict and also stimulates the production of hormones such as vasopressin and aldosterone, which increase blood pressure.

See also ACE inhibitor.

Angiotensin: what is it and how does it affect the human body?

Angiotensin is a peptide that plays an important role in the regulation of blood pressure and homeostasis in the human body. It consists of two peptides: angiotensin I and angiotensin II. Angiotensin I is produced in the liver from the protein alpha globulin under the action of renin, which is secreted by the kidneys. Angiotensin I then passes through the lungs, where it is converted into angiotensin II by the enzyme angiotensin-converting enzyme (ACE).

Angiotensin II is a biologically active peptide that causes blood vessels to constrict and increase blood pressure. In addition, it stimulates the production of hormones such as vasopressin and aldosterone, which also increase blood pressure.

High blood pressure (hypertension) is one of the most common medical problems in the world and can lead to serious complications such as stroke, heart attack and kidney failure. Because of its role in regulating blood pressure, angiotensin is the target of many medications.

For example, drugs called angiotensin-converting enzyme inhibitors (ACEIs) block the conversion of angiotensin I to angiotensin II, which leads to lower levels of angiotensin II in the blood and lower blood pressure. Another class of drugs called angiotensin II receptor blockers (ARBs) block the action of angiotensin II at the receptors, which also lowers blood pressure.

In conclusion, angiotensin is an important peptide regulating blood pressure and homeostasis in the human body. High blood pressure can lead to serious complications, so blocking the action of angiotensin is an effective way to treat hypertension.

Angiotensin is one of the key peptides that regulate the function of the human cardiovascular system. This peptide exists in two forms: angiotensin I and angiotensin II.

Angiotensin I is produced in the liver from the protein alpha globulin by the action of renin, which is produced in the human kidneys. After angiotensin I enters the bloodstream, it passes through the lungs, where it is converted into angiotensin II by the enzyme angiotensin-converting enzyme (ACE).

Angiotensin II plays a key role in the regulation of blood pressure. It causes constriction of blood vessels, which leads to increased blood pressure. In addition, angiotensin II stimulates the production of vasopressin and aldosterone, hormones that also increase blood pressure.

Angiotensin II also affects cardiac contractility and cardiac muscle remodeling. Elevated levels of angiotensin II cause thickening of the vessel walls and an increase in heart mass, which can lead to the development of heart failure.

Due to the important role that angiotensin plays in cardiovascular function, its regulation has become the focus of much research. Some medications, such as angiotensin-converting enzyme inhibitors (ACE inhibitors) and angiotensin II receptor blockers (ARBs), are used to treat hypertension and heart failure.

Overall, angiotensin is an important peptide that plays a key role in regulating the function of the human cardiovascular system. Its regulation can be achieved with drugs such as ACE inhibitors and ARBs, making it a target for the treatment of hypertension and heart failure.