Angizem: an effective calcium channel blocker
Angizem (international name - diltiazem) is a representative of the group of benzodiazepine calcium channel blockers. The drug is used to treat arterial hypertension, angina pectoris and paroxysmal supraventricular tachycardia. Angizem is manufactured by Sun Pharmaceutical Industries Ltd. in India.
The main active ingredient of Angizem is diltiazem. The drug is available in the form of 60 mg tablets. However, there are also retard forms, such as Blockalcin 60, Blockalcin 90, Dilacor XR, Dilcardia retard, Diltiazem hexal retard.
The use of Angizem is based on its ability to block calcium channels in the heart and blood vessels, which leads to vasodilation and a decrease in pressure. In addition, Angizem is able to reduce the heart rate and improve blood supply to the heart.
Angizem is indicated for the treatment of angina pectoris and arterial hypertension. The drug is also used to prevent coronary spasm during coronary angiography or coronary artery bypass surgery. For paroxysmal supraventricular tachycardia, Angizem should be used only intravenously.
It is important to note that Angizem has a number of contraindications. The drug should not be used in cases of hypersensitivity to diltiazem, cardiogenic shock, sinus bradycardia, sick sinus syndrome, sinoatrial and AV block II-III degree, severe aortic stenosis, as well as in children, pregnant and lactating women.
Side effects when using Angizem may include hypotension, bradycardia, headache, dizziness, weakness, peripheral edema, impaired potency, dyspeptic symptoms, hyperplasia of the gum mucosa, allergic reactions and others.
Angizem may interact with other drugs such as carbamazepine, theophylline, cyclosporine A and digoxin. It should also be taken into account that antiarrhythmic drugs and beta-blockers may increase bradycardia, AV conduction disturbances and symptoms of heart failure when using Angizem.
In conclusion, Angizem is an effective drug for the treatment of hypertension, angina pectoris and paroxysmal supraventricular tachycardia. However, before starting to use the drug, you should consult your doctor and become familiar with the contraindications and possible side effects. Also, it is important to follow the dosage recommendations and not combine Angizem with other drugs without first consulting your doctor.