Antiatherosclerotic Agents

Anti-atherosclerotic drugs: On the way to prolonging life

Atherosclerosis is a serious disease that affects the arteries and causes them to narrow, which can lead to serious consequences such as heart attacks. Medicines for atherosclerosis can help fight this disease.

What is atherosclerosis?

*Atherosclerosis* is a progressive non-infectious inflammatory disease that has penetrated into the intima of blood vessels. Progressive loss of the vascular wall, accompanied by the proliferation of connective tissue and the appearance of atherothrombotic plaques within the lumen of the vessel, is the main cause of CVD. Distributed throughout the world. People with unfavorable polygenic heredity, the presence of concomitant diseases of arterial hypertension, type 2 diabetes mellitus and obesity are more susceptible to the disease. Increasing plasma cholesterol levels contributes to increased development of clinically significant ACC. Family history with early development of CVD in the family contributes to the occurrence of ACVD

Atherosclerosis is a disease of the arteries that is characterized by the formation of plaques made of lipids and proteins on the walls of the arteries. These plaques can be hard and irregular, causing the artery to narrow, reducing blood flow and increasing blood pressure. In turn, this can lead to various cardiovascular diseases and reduced life expectancy.

To prevent or slow the development of atherosclerosis, anti-atherosclerotic drugs are used. They can be prescribed both as part of treatment and as prevention for people at risk. The anti-atherosclerotic drug affects several parts of the pathogenesis of the disease, including lipolysis, the formation of endogenous cholesterol and the synthesis of lipoproteins, and also improves metabolism and reduces the hardness and thickness of plaques. These drugs include statins, which block the enzyme responsible for producing cholesterol. Fibrates, such as gemfibrozil, are also used, which reduce blood levels.