Antigen Helminths Eclepsive

Helminth explicit antigens (A. g. e.) are antigens identical to the host antigens and produced by parasites in the process of their adaptation to it. These antigens may be responsible for increasing the pathogenicity of parasites, reducing the reactivity of the host and the development of autoimmune reactions in the host.

The concept of explicit antigens was introduced in 1980 by American immunologist Richard S. Kraus. He suggested that the antigens that are produced by parasites to interact with the host can be different in structure and properties, but they must be completely identical to the antigens of the host. This allows parasites to evade the host's immune response and adapt to its immune system.

A.g.e. may contribute to increased pathogenicity of parasitic organisms, which can lead to the development of severe diseases in the host. For example, some types of helminths can secrete A.g.e. in large quantities, which leads to an increase in their pathogenicity and an increase in the likelihood of complications.

Also A.g.e. can cause autoimmune reactions in the host. This occurs due to the fact that the host’s body begins to attack its own cells and tissues, mistaking them for foreign. This can lead to the development of various autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, etc.

In addition, the presence of A.g.e. in parasites it can reduce the host's reactivity, which can also contribute to the development of autoimmune reactions. This occurs because a parasite that produces A.g.e. can reduce the host's ability to fight infections and other pathogens.

Thus, A.g.e. play an important role in the development of pathological processes caused by parasitic organisms. They contribute to increased pathogenicity of parasites and the development of autoimmune reactions, which can lead to serious diseases in the host. Therefore, the study of A.g.



Helminth explicit antigen What are antigens? Antigens are high-molecular or low-molecular compounds that can specifically interact with proteins of the host's immune system, causing the development of an immune response. Genetic information on immunological reactions is recorded practically in