Anticoagulants

Anticoagulants are medications that prevent blood clotting. They are used for the treatment and prevention of various diseases associated with blood clots, such as deep vein thrombosis, pulmonary embolism, myocardial infarction and others.

The mechanism of action of anticoagulants is based on blocking the activity of blood clotting factors such as thrombin, factor Xa and factor VIIa. These factors play an important role in the formation of blood clots, which can lead to serious illness.

There are several groups of anticoagulants, each of which has its own characteristics of action and application. Some of them are indirect, that is, they do not directly affect the blood clotting process itself, but reduce the ability of the blood to clot. These drugs include warfarin, rivaroxaban, dabigatran and others. Other anticoagulants are direct, meaning they block clotting factors directly. These include heparin and its derivatives, low molecular weight heparins and others.

The use of anticoagulants requires strict dosage control and monitoring of treatment effectiveness. If necessary, it may be necessary to change the dosage or replace the drug with a different type.

It is important to remember that anticoagulants should only be used as prescribed by a doctor and under his supervision. Self-medication can lead to serious complications and even death.



**Anticoagulants** are a group of drugs that have opposite effects on the blood coagulation system in the human body.

We often hear from our family and friends that the concentration of one or another coagulation factor is increased in their blood. Most of us sincerely believe that since the blood is “thick”, it must be washed, the blood must somehow be diluted, liquefied, because the clot is dangerous for the patient’s life. It is these misconceptions that cause pathological bleeding in people. But in cases where the coagulation system functions adequately, the blood should clot when damaged - this is how nature took care that gaping wounds that would be open to infection would not form in the wounds, but blood clots would form, stopping the bleeding and healing the tissue defect.

What are anticoagulants? At home, when bleeding, many people stop the bleeding using improvised methods: they put napkins with hydrogen peroxide into the wound, prick blood vessels there, remove it with a plaster, press it tightly, sprinkle it with calcium (lime or ash is also used). In clinics and hospitals, such treatment methods are used by medical students. So they are fundamentally mistaken. The hemostatic effects of such methods are very short-lived, and they are incapable of stopping dangerous bleeding, because after the multifactorial effect on the capillary is stopped, it is reanimated very quickly. That is, the coagulation continues, but manipulations that stop it can lead to sad