Pharm-Group: Immunoglobulins
International name: Antithymocyte immunoglobulin
Synonyms: Antilympholin, Antilympholin Kz, ATG-Fresenius (Anti-human T-lymphocyte-globulin of rabbit), ATG-Fresenius S, Atgam, Thymoglobulin
Ingredients: Antithymocyte immunoglobulin.
Indications for use: Kidney transplantation, prevention of graft rejection during skin grafting. Aplastic anemia in the absence of indications for bone marrow transplantation.
Contraindications: Hypersensitivity to the drug, pregnancy, lactation, childhood.
Side effects: Allergic reactions, thrombocytopenia, leukopenia, granulocytopenia, anemia, pancytopenia, enlarged or ruptured spleen, arterial hypertension, heart failure, pulmonary edema, nausea, vomiting, diarrhea, gastrointestinal bleeding, perforation of the stomach or intestines, ulceration of the oral mucosa , pain in the abdomen and epigastric region, headache, weakness, convulsions, confusion, loss of coordination, dizziness, fainting, paresthesia, swelling at the infusion site, thrombophlebitis, nosebleeds.
Interaction: No data available.
Overdose: No data available.
Special instructions: For use only in hospital settings. Treatment is stopped in the presence of a generalized rash, tachycardia, dyspnea, collapse, anaphylaxis, persistent leukopenia in patients with a kidney transplant. More detailed information can be found in the instructions for use of the drug.