Argentaffinocytes Intestinal

Intestinal argentaffinocytes: role and functions

Intestinal argentaffinocytes, also known as argentaffin cells, argentophilic cells, basal granular cells, yellow cells, enterochromaffin cells, Kulczycki cells or enterochromaffinocytes, are special types of cells that populate the intestinal mucosa. In this article we will look at the role and functions of intestinal argentaffinocytes.

Intestinal argentaffinocytes are neuroendocrine cells, which means they perform both neural and endocrine functions. These cells contain granules that are stained with argentaffin methods such as the Gomori method or the Von Kupffer method. Argentaffinocytes are located in the lower part of Lieberkuhn's crypts, which are concave structures on the surface of the intestinal mucosa.

One of the main functions of intestinal argentaffinocytes is the secretion of biologically active substances such as serotonin, histamine and other peptides. Serotonin plays an important role in the regulation of intestinal motility and is involved in the transmission of nerve impulses. Histamine also plays a role in neurotransmission and immune response.

In addition, intestinal argentaffinocytes are involved in the regulation of appetite and the production of hormones such as gastrin, secretin and cholecystokinin. Gastrin stimulates the secretion of gastric juice and enhances the motor activity of the stomach, and secretin and cholecystokinin regulate digestive processes, affecting the secretion of digestive enzymes and juices.

It is interesting to note that intestinal argentaffinocytes can also perform a protective function in the case of various pathological conditions. For example, during inflammatory processes or tumors, they can release certain substances that promote the immune response and regeneration of damaged tissue.

In conclusion, intestinal argentaffinocytes are important cells playing a role in the intestinal neuroendocrine system. Their unique ability to release biologically active substances and regulate various processes makes them key players in digestion, appetite regulation, immune response and body defense. Further studies of intestinal argentaffinocytes will help to better understand their precise mechanisms of action and their role in various intestinal diseases, opening opportunities for the development of new diagnostic and treatment methods.

Intestinal argentaffinocyte (argentaffin + histamine) (IAC) is a type of intestinal epithelial cell that is part of the body's neuroendocrine system. CCAs have granules containing histamine and are not normally visible to the naked eye. However, when their granules undergo breakdown, these granules become lighter in color and become more visible and are called basal granules or yellow granules. Such changes can be observed in a number of intestinal diseases.

CCs are nerve and hormonal cells that contribute to the functioning of a number of