Ascentra

Country of origin - Slovenia
Pharm-Group - Antidepressants - selective inhibitors of neuronal uptake

Manufacturers - Krka d.d. (Slovenia)
International name - Sertraline
Synonyms - Zoloft, Sirlift, Stimuloton, Thorin
Dosage forms - film-coated tablets 100 mg, film-coated tablets 50 mg
Composition - Active substance - sertraline.

Indications for use: Depression, obsessive-compulsive disorders.

Contraindications - Hypersensitivity, childhood, breastfeeding (stop during treatment).

Side effects - Impaired consciousness, generalized convulsions, migraine, dizziness, sleep disturbance, aggressiveness, amnesia, depersonalization, emotional lability, euphoria, withdrawal syndrome, headache, tachycardia, arterial hypertension or hypotension, allergic skin reactions.

Interaction - When prescribed together with MAO inhibitors, it causes hyperthermia, irritability, and impaired consciousness. Promotes the accumulation of H1 blockers.

Overdose - Symptoms: drowsiness, anxiety, nausea, vomiting, tachycardia, ECG changes. Treatment: activated charcoal, gastric lavage, forced diuresis, maintenance of vital functions.

Special instructions - If the patient is taking antidepressants of other groups (MAO inhibitors, tricyclics), then sertraline can be prescribed only 2 weeks after their discontinuation.

Literature - Encyclopedia of Medicines 9th edition 2002.