Aspivatrin

Country of origin: Russia
Pharm-Group: Anti-inflammatory drugs - salicylic acid derivatives

Manufacturers: Vatra (Russia)
International name: Acetylsalicylic acid
Synonyms: HL-Pain, Anopyrin, Apo-Asa, Aspecard, Aspicor, Aspilight, Aspirin, Aspirin "York", Aspirin "Quality", Aspirin 1000, Aspirin for children, Aspirin cardio, Aspirin UPSA, Aspirin-Direct, Aspitrin, Aspomay , Aspro 500, ACC-Ratiopharm, Acenterin, Acesal, Acetyline, Aspivatrin, etc.
Dosage forms: effervescent tablets 250 mg, effervescent tablets 500 mg
Composition: Active substance - acetylsalicylic acid.

Indications for use: Rheumatism, rheumatoid arthritis, infectious-allergic myocarditis; fever in infectious and inflammatory diseases; pain syndrome of various etiologies: headache (including those associated with alcohol withdrawal syndrome), migraine, toothache, neuralgia, myalgia, arthralgia, algomenorrhea; thrombosis and thromboembolism (prevention), myocardial infarction (secondary prevention), coronary heart disease, unstable angina, cardiac arrhythmias, etc.

Contraindications: Hypersensitivity, erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, gastrointestinal bleeding; "aspirin" asthma; bleeding disorder, vitamin K deficiency, severe renal failure, first trimester of pregnancy, lactation. It is prescribed with caution to patients with gout, liver diseases, and children under 12 years of age with hyperthermia due to viral diseases.

Side effects: Nausea, anorexia, gastralgia, diarrhea, erosive and ulcerative lesions, bleeding in the gastrointestinal tract; allergic reactions (skin rash, bronchospasm); renal and/or liver failure; thrombocytopenia. With long-term use - dizziness, headache, reversible visual impairment, tinnitus, vomiting, bleeding, etc. Decreased sense of hearing acuity, tinnitus, severe headaches - in high doses. In predisposed patients - bronchospasm.

Interaction: Strengthens the effect of heparin, oral anticoagulants, reserpine, steroid hormones and oral antidiabetic agents. Reduces the effect of antihypertensive drugs. Simultaneous administration with other non-steroidal and anti-inflammatory drugs, methotrexate increases the risk of side effects.

Overdose: Symptoms: salicylic syndrome (nausea, vomiting, tinnitus, general malaise, fever - a poor prognostic sign in adults). More severe poisoning - stupor, convulsions and coma, non-cardiogenic pulmonary edema, acid-base imbalance, increased body temperature.

Special instructions: 5-7 days before surgery, it is necessary to stop taking the drug (to reduce bleeding during surgery and in the postoperative period). During long-term therapy, it is recommended to regularly perform blood tests and examine stool for occult blood.

Literature: Encyclopedia of Medicines, 9th edition, 2002. Medicines M.D. Mashkovsky 14th edition.