Country of origin: Russia
Pharm-Group: Antibiotics - macrolides and azalides
Manufacturers: Synthesis AKO, Kurgan (Russia)
International name: Azithromycin
Synonyms: Azivok, Azitral, Azitrox, Azithromycin, AzitRus, Vero-Azithromycin, Zi-Factor, Zimax, Zitrolide, Zitrolide forte, Zitrocin, Sumazid, Sumamed, Sumamed forte, Sumametsin, Sumamox, Hemomitsin
Dosage forms: capsules 250 mg
Composition: Active substance - azithromycin.
Indications for use: Infections of the upper and lower respiratory tract (streptococcal pharyngitis and tonsillitis, bacterial exacerbation of chronic obstructive pneumonia, interstitial and alveolar pneumonia, bacterial bronchitis), ENT organs (otitis media, laryngitis and sinusitis), genitourinary system (urethritis and cervicitis) , skin and soft tissues (erysipelas, impetigo, secondary infected dermatoses), chronic stage of erythema migrans (Lyme disease).
Contraindications: Hypersensitivity to macrolides, severe liver dysfunction, pregnancy, lactation.
Side effects: Nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea, melena, cholestatic jaundice, chest pain, palpitations, weakness, drowsiness, headache, dizziness, nephritis, vaginitis, candidiasis, neutropenia or neutrophilia, pseudomembranous colitis, photosensitivity, rash, angioedema, eosinophilia; in children, in addition, hyperkinesia, agitation, nervousness, insomnia, conjunctivitis.
Interactions: Antacids containing aluminum or magnesium hydroxide reduce absorption and maximum concentration.
Overdose: No information.
Special instructions: Use with caution in cases of severe dysfunction of the liver, kidneys, cardiac arrhythmias. After discontinuation of treatment, hypersensitivity reactions may persist in some patients, which requires specific therapy under medical supervision.
Literature: Encyclopedia of Medicines 2002.