Azobelki

Azo proteins are products of the interaction of proteins with compounds containing diazonium. They are modified forms of the original proteins that can be used in immunology and allergology research.

Diazonium compounds, such as nitrosotriacetic acid (NTA) or nitro-bis(2-ethylhexyl)amine (NHEHA), are capable of interacting with amino acids in proteins, changing their structure and antigenic specificity. This can lead to the emergence of new antigenic properties in the protein, which can be used in the diagnosis and treatment of various diseases.

Azoproteins can be used to create vaccines, diagnose infectious diseases, and identify allergens. For example, azoproteins derived from proteins associated with peanut allergy can be used as allergens for the diagnosis and treatment of this allergy.

However, the use of azoproteins can also have negative consequences. Some azoproteins can be highly toxic and cause serious side effects in patients. Therefore, when using azoproteins in medical research and diagnostics, strict safety and quality control regulations must be followed.

Introduction

Azoproteins are products of the interaction of proteins with diazonium compounds, characterized by altered antigen specificity compared to the original protein, and are used in science (immunochemistry) for research. This group includes azobenzenediones, azophenanthrolines, azoquine and other azomethylene compounds of different groups that can combine with proteins. Antigens are foreign substances to the body that can cause an immune response (subject to infection), the antibodies they produce and a state of immunity (immunity). Antigens are the basis of substances for vaccines. The resulting complexes of a protein and an antigen specific to it are called analogue antigens; they are used in pharmacology to prevent anaphylaxis, as well as to dissolve blood clots. To identify individual proteins, similar proteins with altered structural features, so-called protein co-agonists and other antibodies, are also used. They are produced by mixing