Basophile

Basophil

Basophil is a type of leukocyte (white blood cell), which is characterized by the presence of large granules in the cytoplasm. These granules stain purple-black when the cytoplasm is exposed to Romanowsky dye.

The purpose of basophils in the human body is not yet fully understood. However, it is known that they are capable of absorbing foreign particles, and also contain histamine and heparin. Histamine is involved in inflammatory reactions, and heparin prevents blood clotting.

Normally, one liter of blood of a healthy person contains from 30 to 150 million basophils. An increase in their number may indicate various pathological processes in the body.

Basophil: description and functions

Basophils are a type of white blood cell (leukocyte) that have large granules in the cytoplasm that turn purple-black when exposed to Romanowsky dye. They were discovered in 1879 and first described as cells of unknown function. Today we know that basophils play an important role in the immune system.

Basophils make up less than 1% of all white blood cells in the blood, and their number can vary depending on various factors such as allergic reactions, infections and stress. Typically, one liter of blood contains 30-150x10^6 basophils.

One of the main functions of basophils is participation in allergic reactions. When a person encounters an allergen, such as pollen or food, basophils are activated and release their granule contents, including histamine and other biologically active substances. Histamine causes capillaries to dilate and increase vascular permeability, leading to allergy symptoms such as itching, redness and swelling.

In addition, basophils are capable of engulfing foreign particles such as bacteria and viruses through a process called phagocytosis. This function of basophils is not as well understood as their role in allergic reactions.

Basophils also contain heparin, an anticoagulant that helps prevent blood from clotting at the site of infection, allowing immune cells to spread in the desired direction.

Although basophils have an important role in the immune system, their functions are not fully understood. Some studies have shown that basophils may play a role in various diseases such as asthma, allergic rhinitis, dermatitis and rheumatoid arthritis.

In conclusion, basophils are a type of white blood cell that play an important role in the immune system. They are able to absorb foreign particles, contain histamine and heparin, and are involved in allergic reactions. Although much is still unknown about the functions of basophils, they are important players in the body's fight against infections and other diseases.

Basophils are also called non-activated immune cells. Basalfas are involved in the regulation of blood pressure, pain perception, and are responsible for the body’s defense reactions (histamine levels increase).

Basophils play an important role in the functioning of the human immune system. They take an active part in the development of an allergic reaction. In patients with asthma, the cell content is higher than normal, while in healthy children there is a deficiency. In childhood, diseases often occur due to disturbances in the functioning of the immune system.

Why is a decrease in granulocytes dangerous? It is believed that a decrease in their level in the blood indirectly indicates the development of a pathological process. One of the serious pathologies accompanied by their decrease is nephrotic syndrome, when there is a high level of lipoproteins in the blood. Besides